Citalopram and weed

Citalopram and weed

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The current blogspot will be based on the drug interaction of citalopram and weed. We will discuss how weed intake while using citalopram affects the efficiency of citalopram as an antidepressant. We will also learn the adversities of taking weed while being treated with citalopram.

Can we take weed while being on citalopram?

Weed is often used as a source of recreational drugs and is also used for substance abuse. Weed comes from the root source of the cannabis plant. It is commonly available with the names of weed, pot, dope, grass and marijuana.

Usually people take weed through the following ways:

  • Weed is used by smoking it 
  • Weed is used by drinking it
  • Weed is used by vaping it
  • Weed is often eaten directly

Weed has a tendency to alter the brain’s state of consciousness. Weed often has mind altering compounds that can affect a person’s brain and body. Weed has a natural tendency for addiction and that is why  it is a drug of choice for recreational parties and for addiction. Weed is injurious to human health and may lead to death if unmonitored doses are taken.

Tetrahydrocannabinol is an active ingredient in weed. This acts as a stimulant for activating the part of the brain related to pleasure seeking and adventure. This is the main reason for feeling high after taking weed or any other forms of cannabis.

Weed is often used by the patients of depression for its known effects of  relaxation and calmness. The use of weed as a recreational drug and for reducing the levels of negative feelings is thus more among the depressed and anxious individuals as compared to the non depressed people.

Citalopram is a drug that is used as antidepressant and belongs to the the class of selective serotonin reuptake inhibitors. Citalopram is commonly used by mental health providers for treating depression and panic attacks among individuals. 

The results of citalopram include a balanced serotonin in the body. Citalopram helps in regulating mood, sleep and other voluntary functions of the body that are disturbed due to depression.

The citalopram as an antidepressant changes the rate of reabsorption of serotonin neurotransmitters into the body. Thus the brain’s chemistry gets changed for the better. The balanced state of neurotransmitters in the brain results in an enhanced mood, increased sleep and better appetite.

Citalopram also reduces the panic attack symptoms in the human body. If an individual is going through panic attacks associated with depression, the intake of citalopram helps reduce the associated mood symptoms and physical activity levels.

The food and drug regulatory authority has recommended not to combine citalopram intake with weed. Inhaling, snorting, drinking or eating weed in raw form or combined with any other compound can lead to deterioration of the purpose of citalopram intake. 

Weed taken along citalopram medicines results in adverse reactions in the body that combine the side effects of both the citalopram drug and weed.

The use of psychoactive agents like weed and a psychotropic drug like citalopram is not much appreciated and has been known to produce adverse conditions. The psychoactive agents usually disturb the efficacy of psychotropic drugs. Thus weed use in depression patients being treated with citalopram can disturb their course of treatment.

What happens in our body if we take citalopram with weed? 

Taking weed in any of its forms while being treated with citalopram tends to enhance the negative effects of citalopram and weed on our body. 

The side effects of citalopram alone include the following:

  • Allergic reactions to the drug
  • Nausea
  • Vomiting
  • Hallucinations
  • Seizures
  • Increased suicidal thoughts
  • Pounding heart
  • Odd behaviors

On the other side, the weed due to its main active ingredient tetrahydrocannabinol leads to :

  • A “high” state of pleasure and elated mood
  • Increased need for thrill and adventure leading to risky behaviors due to increased dopamine
  • Snorting weed takes a direct absorption into the bloodstream and leads to a state of quick high.
  • With the use of weed, an individual’s mental health is greatly affected. 
  • Individuals feel unable to function appropriately in social settings
  • Weed intake leads to disturbed cognitive functioning
  • Weed leads to poor judgement abilities and planning skills
  • Individuals often feel paranoid or suspicious due to weed intake
  • Weed tends to intensify an individual’s senses
  • Weed often leads to psychomotor agitation
  • Weed has a potential to decrease a person’s inhibition and thus involves a risk of getting involved into risky and life threatening behaviors including sexual behaviors
  • The common side effects of weed include tachycardia, nausea, confusion, dizziness, indecisiveness, vomiting and anxiety.

If an individual drinks, eats, smokes or snorts weed while being treated with citalopram, the interaction may lead to worsening of the side effects of both the individual drugs. As a result the individual will have the following symptoms:

  • The interaction of citalopram and weed lead to an increased heart rate among individuals.
  • Citalopram and weed lead to poor executive functioning among individuals
  • Weed intake while being on citalopram leads to panic attack as anxiety and nervousness is a side  effect of both the drugs
  • Weed intake is related to dizziness and confusion, citalopram and weed combined may result in low levels of concentration  thus a person may feel difficulty in maintaining appropriate gait or driving a car.
  • Hallucinations and paranoid thoughts are often an adverse effect of citalopram and weed combination
  • Psychomotor agitation is also an effect of weed and citalopram interaction among individuals.
  • The weed intake leads to more citalopram hanging in the body and thus can lead to an exaggerated buildup of citalopram in the body that is unmonitored.


The current blogspot focused on the drug interaction of citalopram and weed. We learned the adversities of weed intake while being treated with citalopram. We also discussed the health risks of the combination of citalopram and weed among humans.

Frequently asked questions (FAQs): Citalopram and weed 

Can I smoke while taking citalopram?

Smoking tends to reduce the blood sugar levels and also reduces the effects of pirfenidone. So if you are a smoker, try to quit smoking before starting treatment with citalopram.


Does weed interact with any medications?

Weed may have serious interactions with drugs including:

  •  warfarin resulting in increased international normalized ratio and risk of bleeding
  •  clobazam resulting in increased risk of benzodiazepine toxicity
  • central nervous system depressants and sympathomimetics resulting in additive effects

What should you not take with citalopram?

You should not take citalopram with the following :

  • buspirone (Buspar®)
  • fentanyl (Abstral®, Duragesic®)
  •  lithium (Eskalith®, Lithobid®)
  • methylene blue injection
  • Tryptophan
  • St. John’s wort
  • amphetamines


Does weed increase serotonin?

At lower doses, cannabis is known to increase the levels of serotonin in the human body.



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