Does Kalms contain St.John’s wort?

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This blog post will explore whether Kalms tablets contain St. John’s Wort. 

We will also briefly discuss what Kalms is, what it is used for, the different kinds of kalms and the key ingredients used in Kalms. 

Does Kalms contain St.John’s wort?

No. Kalms does not contain St.John’s Wort also scientifically known as Hypericum perforatum.

Instead Kalms pride itself of being one of the most potent herbal medications made of various herbs to help relieve stress and induce sound and good quality sleep for its users. 

The Kalms tablet’s ingredients tend to differ according to the kind of Kalms tablet that is being referred to by the key ingredients of Kalms is Valerian root, hop strobiles which are flowers of the hop plant Humulus lupulus, and extract Gentian root.

  • Valerian (Valeriana officinalis) is an herb found originally in Europe and parts of Asia and is known for its sedative effects on the brain and nervous system. 

Valerian has been used as a traditional medicine dating back to ancient Greeks and is commonly used to manage insomnia and sleep disturbances. 

Valerian may also be used for anxiety and stress, however there is not enough scientific evidence to support its use. 

Some common side effects of this herb include dizziness, drowsiness, headache, stomach upset, mental dullness, and vivid dreams. 

  • Gentian root is derived from the Gentiana genus, a flowering plant found in the highlands in parts of Europe, Asia, and the Americas. Though the flower of the plant is beautiful, only it’s roots are used for medical purposes. 

The root is usually dried and made into pills, teas, tinctures, and extracts and either topically applied with a plaster or consumed as a drink.

  • Hops are the dried, flowering parts of the hop plant (Humulus lupulus), commonly used as a medicinal plant for various remedies; however, evidence of health benefits is limited. 

Hops contain many chemicals that seem to act similarly to the hormone oestrogen while other chemicals in the plant seem to cause sleepiness.

What is St.John’s Wort?

John’s wort scientifically known as Hypericum perforatum is a flowering shrub native to Europe. 

It has been named as such because of the fact that this plant bloomed around the time John The Baptist, a biblical saint, was born.

The plant’s flowers and leaves are used for its active ingredients such as hyperforin and the pant’s medicinal properties are used to treat depression and menopausal symptomst.

Many experts push the idea that St.John’s Worts acts similar to antidepressants where it has the property to increase the brain chemicals such as serotonin and noradrenaline’s levels which in turn regulate mood. 

Clinical trials and research has found that St. John’s Wort is found to be slightly more effective than placebos for the treatment of mild to moderate depression only and must not be used for treating severe depression nor should it be a replacement for other pharmacological treatments for depression. 

When drugs made of this particular plant in small dose for a short period of time, it is considerate safe with very mild side effects such as:

  • Agitation and anxiety
  • Dizziness
  • Diarrhoea, constipation and stomach discomfort
  • Dry mouth

Experts conclude that this particular drug or drugs made of this plant must not be used with other drugs and antidepressants as it can lead to serotonin syndrome due to high levels of serotonin in the body.

It is also important to note that St.John’s wort can weaken the impact of other drugs and treatments such as:

  • Antidepressants
  • Birth control  pills
  • Cyclosporine, used to prevent the body from rejecting transplanted  organs
  • Digoxin, a heart  medication
  • Oxycodone, a pain medicine
  • Some HIV drugs, including indinavir
  • Some cancer medications, including irinotecan
  • Warfarin, an anticoagulant (blood thinner).

Due to this impact of the herb on other treatments, it is important that you do not self-medicate with this plant. If you are using drugs made of this plant, you must notify your doctor before being put on any other treatments. 

Can Kalms and St.Johns wort be used together?

When it comes to the use of Kalms and St. John’s Wort, it must be mentioned that using the drug can cause an increase in side effects related to dizziness, drowsiness, confusion, and difficulty concentrating due to the presence of Valerian root properties. 

In older adults, they might experience Cognitive impairment such as difficulty thinking, judgement, and motor coordination. 

It is important that you and your doctor have a detailed discussion on your use of either of these two drugs or drugs with these ingredients before being put on either of them as there can be some interaction between the two. 

What is Kalms?

Kalms Tablets are traditional natural drugs designed for relief of signs associated with:

  • Stress (e.g mild anxiety, worry, irritability)
  • Menopause (e.g flushings, worry, wakefulness, cold sweats)
  • Sleeping problems, promoting natural sleep

It is important that before you use the tables to ask your doctor or pharmacist if you can take Kalms tablets when taking other prescription medicines or medicines without a prescription.

What are the different Types of Kalms?

There are a variety of Kalms products such as:

  • Kalms Night One-A-Night
  • Kalms Night
  • Kalms Day
  • Kalms Lavender One-A-Day Capsules

What is Kalms made of?

Here are the descriptions of the key ingredients used in Kalms tablets:

Kalms Night One-A-Night

The active Ingredient of this kind of Kalms Tablet is Dry Extract from Valerian Root (Valeriana Officinalis L.) along with  Ethanol 60% V/V 385mg as the solvent. 

Kalms Night

The active substance per tablet is Dry extract from Valerian root – 96 mg, (Valeriana officinalis L.) with Ethanol 60%v/v as the solvent.

The other ingredients include Croscarmellose Sodium, Magnesium Stearate, Silicified Microcrystalline Cellulose, Talc and Silicon Dioxide in the core while the Coating of the tablet contains Hypromellose, Talc, Titanium Dioxide, Macrogol, Saccharin Sodium.

Kalms Day

Active Ingredients of the day tablet is 33.75mg of Dry Extract from Valerian Root (Valeriana Officinalis L.) and Ethanol 60% v/v, along with Sucrose.

Kalms Lavender One-A-Day Capsules

Active Ingredients is 80 mg of oil from flowering tops of Lavender (Lavandula angustifolia Miller, aetheroleum) and also contains Sorbitol. 

Kalms Lavender One-A-Day capsules are the only type of Kalms tablet that has Lavender instead of Valerian as the main component. 

How to take Kalms tablets?

To use Kalms tablets to help relieve symptoms associated with stress such as mild anxiety and irritability or symptoms that are associated with menopause, it is important that you talk to your physician about the dosage. 

The adult recommended dosage will be mentioned on the instructions leaflet depending on the type of Kalms tablets you are taking in. The recommended dose for adults and the elderly is 2 tablets 30 to 60 minutes before bedtime.

It is not recommended for children under the age of 12 years old since there is limited research on how kalms impact younger individuals. 

The oral drug is for short term use only and must not be taken as a lifelong treatment to aid with stress, insomnia, and anxiety. 

The tablets should be swallowed whole with water or other liquid

This medicine should be taken for 2-4 weeks continuously. The maximum daily dose is 6 tablets and one should not take more than six a day.

What are the side effects of Kalms?

Even though this is considered a natural and herbal remedy. Valerian root and other herbal remedies can cause side effects. 

While not everyone will experience the same side effects or effects of the medication, it is important to be aware of the reactions it might cause. 

Side effects include:

  • Gastrointestinal effects such as nausea and stomach cramps.
  • Gastrointestinal disorders have been observed with Gentian roots.
  • In rare cases, tachycardia (heart palpitations) and pruritus have been reported. 
  • Headaches.
  • Lavender might cause burping and skin reactions like itching and hives. 

How long do kalms stay in your system?

The answer to the question “How long do Kalms stay in your system?” may depend on the dosage that you have ingested and individual factors such as body weight of the individual. 

According to, a dose of valerian extract 600 mg in healthy subjects was highest in concentration after 30 mins to 2 hours after ingestion. With elimination half life after 2 to 3 hours and completely gone after 5 hours.

Who shouldn’t use Kalms?

Some people who have the following conditions should not use Kalms and should consult a doctor for an alternative medication to help treat their ailments. 

  • People with any type of infection (including HIV, malaria, or tuberculosis);
  • Should not be used to treat anxiety or depression;
  • People with asthma or allergies;
  • Cancer Patients;
  • Should not be used to treat erectile dysfunction
  • People with Heartburn or gastroesophageal reflux disease (GERD);
  • With high blood pressure, high cholesterol, or a heart condition;
  • migraine headaches
  • psoriasis, rheumatoid arthritis, or other autoimmune disorders;
  • People who have a medical history of epilepsy and Seizures.


This blog post has explored whether Kalms tablets contain St. John’s Wort. 

We have also briefly discussed what Kalms is, what it is used for, the different kinds of kalms and the key ingredients used in Kalms. 

FAQ related to Does Kalms contain St.John’s wort?

Is St John’s wort the same as valerian?

No, St.John’s wort and Valerian are two different plants. 

St. John’s wort (Hypericum perforatum) is a herbal medicinal plant often used for the treatment of depression whereas Valerian (Valeriana officinalis) is a herb used to relieve insomnia and restlessness.

When should you not take kalms?

You should not take Kalms in the following scenario:

  • If you are under 12 years old. 
  • If you are pregnant, trying to get pregnant, or breastfeeding. 
  • If you have missed a dose and are close to the next dose, wait for the next dose to avoid double dosing. 
  • If you are about to drive
  • If you are drinking alcohol
  • If you are about to use heavy machinery.

Who should not take kalms?

The use of this product in children or adolescents under 12 years of age is not recommended because research  data on its effect on younger children is not sufficient.

Can St John’s wort make anxiety worse?

Because St.John’s wort is a stimulant used for the treatment of depression, it can cause individuals with anxiety to experience more anxiety and worsen feelings of anxiety in some people. 

Can you take vitamin D with St John Wort?

There is limited studies done of the interaction between Valerian and Vitamin D however, 

There has been no interactions found between st. John’s wort and Vitamin D3 that proves to be harmful as of yet provided that both drugs are used appropriately and under the supervision of a medical doctor. 

Should I take St John’s wort in the morning or at night?

It is advised that because St.john’s wort causes some side effects such as trouble sleeping, vivid dreams, restlessness it is advisable that it be used in the morning due to its impact on sleep. 

Can you take multivitamins with St John Wort?

St.John’s wort can interact with other drugs, herbs, and supplements. So if you are going to take multivitamins with St.John’s wort, talk to your doctor and make sure you avoid drugs that can increase levels of serotonin in your body as it can lead to higher risk of serotonin syndrome. 


Kalms Day Tablets. Click2Pharmacy.Retrieved on 21st January 2022.

Drug Interactions between st. John’s wort and Valerian Root. Retrieved on 21st January 2022.

St John’s wort – Hypericum perforatum. Retrieved on 21st aury 2022.

St. John’s wort. Mayo Clinic. Retrieved on 21st January 2022.

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