How long does it take for Vraylar to work?

As a BetterHelp affiliate, we may receive compensation from BetterHelp if you purchase products or services through the links provided.

In this article, we will be answering the question, “ how long does it take for Vraylar to work”, Vraylar, precaution to be taken before medication, side effects of it, the working mechanism of the medication, dosage, alternative to Vyalar, Interaction with other drugs, overdose effect and concluding with some FAQs concerning the topic.

how long does it take for Vraylar to work

For Vraylar to work, it takes time and the patients tend to observe or notice the gradual reduction or lessening of the severity of symptoms in a few weeks.

  • The longer the medicine is taken, the severity symptoms lessen and there is gradual recovery.


Vraylar is under the generic name of Cariprazine which is usually used to treat mental disorders such as mood disorders, bipolar disorder, depression and schizophrenia. It belongs to the class of Atypical Antipsychotics.  Second generation. It is mostly used for the treatment of Schizophrenia in the adult population. Vraylar contains the active drug Cariprazine. 

However, in the case of geriatric population with dementia-related psychosis, the use of Vraylar is not approved yet. 

Working of Vraylar

Vraylar worked by restoring the balance of certain natural substances or neurotransmitters in our brains such as Serotonin and Dopamine.

However, the exact working mechanism of Vraylar is unknown.

Uses of Vraylar

Vraylar is used for the treatment of Schizophrenia majorly, however, it can also be used for the treatment of Depression, Bi-Polar Depression and other mental illnesses. 

Following are the uses of Vraylar:

  • Decrease hallucination in the schizophrenia patients
  • Helps in thinking more clearly and positively
  • Reduce agitation
  • Treatment of acute manic and mixed episodes.
  • Improve our mood, thinking and behaviour
  • Reduce the severity of the mental condition

Precautions Before taking the medicine

Before taking Vraylar, the patient needs to take it is important for the patient to take the precaution of certain things so that one doesn’t need to go through the side effects of the drug. 

Few of the precaution one need to follow are:

  • Report if the person has an allergic reaction
  • Poor blood flow in the brain such as stroke
  • Diabetes running in the family
  • Cardiac problem 
  • High blood pressure
  • Problem with the nervous system functioning
  • Low white blood cell count
  • Alcohol or Marijuana user
  • If the person engages in hardcore exercises or activities
  • An older adult with an underlying memory-related problem
  • Untreated mental as well as mood disorders
  • Pregnancy plan and fetus in womb
  • Breastfeeding

So these are the precautions one needs to take care of before taking the medicine. One should also make sure that they consult their doctor or psychiatrist before starting the medication. 

The side effect of Vraylar

Vraylar can cause either mild or severe side effects. The duration of the symptoms depends on the severity, it ranges from several weeks to months. 

Mild Side Effect

It is not that severe and doesn’t last long and go away in a few days, however, if it gets serious, one needs to consult a doctor. 

These side effects include:

  • Involuntary muscle movements such as twitching and twisting movement
  • Slow and Trouble in movement
  • Muscle stiffness
  • Dizziness
  • Headache
  • Increase in the production of saliva
  • Sleepy and tiredness
  • Gain in weight
  • Nausea or Vomiting.
  • Lightheadedness
  • Constipation
  • Tremor and Muscle spasm

Serious side effects

The serious effects of Vraylor don’t result in most of the patients but there are cases of its occurrence. These symptoms are severe and one should report to the doctor if they experience any of it. 

Some of the serious side effects include:

  • Hypotension and drop in blood pressure
  • A problem in controlling body temperature
  • Neuroleptic malignant syndrome: including high fever, sweating, rapid breathing, racing heartbeat, confusion and drowsiness.
  • Low white blood cell count
  • High blood sugar and cases of diabetes
  • Blurred vision
  • Cholesterol and high fats in the blood
  • Seizures and loss of consciousness.
  • Trouble in swallowing and breathing
  • Tardive Dyskinesia: involuntary and repetitive movement 
  • Suicidal thoughts and behaviour: it is found to be the highest and most severe during the first few months of taking the antidepressant.
  • Akathisia: the feeling of restlessness and desire to move around, fidgeting and pacing.
  • Increased risk of death with psychosis: those senior citizens with underlying dementia-related disorders are at higher risk of death after taking antipsychotic drugs like Vraylar.

Mentioned are the side effects of Vraylar of which some of it requires medical attention while others fade away after taking the medicine for some time. Most of the side effects go away during the span of treatment while someone needs to report to health care professionals. 

Dosage of Vraylar

The capsule dose of Vraylar starts from 1.5mg to 6mg. It is usually given once a day that can be taken with or without food. 

Dosage of it depends on several factors such as

  • Age of the patient
  • Type and severity of the condition 
  • Other underlying medical condition
  • Medication one is already taking.

Dosage for Depressive episodes in Bi-Polar DIsorder

For the treatment of Depressive episodes in Bi-Polar Disorder, the starting dose is 1.5mg. Doctor at times increases the dose to 3mg after 15 days of medication. It is taken once a day.

Dosage for Manic or Mixed Episodes in Bi-Polar Disorder

The typical dosage for Vraylar is 3mg to 6mg once a day. One can gradually increase the dose from 1.5mg to 3mg and more.

Dosage for Schizophrenia

For the treatment of Schizophrenia, the typical dose starts from 1.5mg-6mg once a day. The maximum dose is 6mg a day. 

Adjustment of dose based  on the side effects

When on the higher dose of Vraylar, there is more side effect and it gets more severe on the consumption of more dose. The modification or adjustment of the dose depends solely on the recommendation of the doctor.

Working of Vraylar and duration

The working of Vraylar for different mental disorders varies and the duration of recovery and reduction in symptoms tends to differ based on the individual case.

  • Schizophrenic Patient

For a patient with Schizophrenia, within the first 2 weeks, hallucination, disorganised thinking and the delusion improve.

After 1-2 weeks of medication, the patient gets motivated to meet people and be around them.

By the sixth week of medication, there is a significant recovery in the patient after taking Vraylar.

  • Patient with Manic or Mixed Episode with Bi-Polar

Patient with Manic or Mixed Episodes associated with Bi-polar disorder, within 3 weeks of medication, there is a significant reduction in the symptoms.

  • Patient with Depressive Episodes with Bi-Polar Disorder

Within 6 weeks of medication of 1.5mg, there is a reduction in the symptoms.

Interaction with Drug

Interaction with a certain drug changes the working of the drug as well as increases risk of certain side effects. 

Metoclopramide majorly interacts with Vraylat and results in serious side effects.

Some other drugs that interact with it are abametapir, apalutamide, chloramphenicol, hydrocodone, etc, etc. 

Discontinuation of the drug

Discontinuing the drug results in a decline in the concentration of plasma and metabolism.

Vraylar and Abilify

Vraylar is a capsule that one has to swallow and can take once a day while Abilify is a tablet that also has to take once a day but it’s not available anymore.

Both of them are second-generation atypical antipsychotic drugs having similar side effects.

Both of them are approved and effective for different disorders. For schizophrenia, both drugs can be used for treatment.

Vraylar contains Cariprazine and both of them have a common brand name drug.

Alternatives to Vraylar

Since it is a second-generation antipsychotic, other drugs that can be used for the similar effect of Vraylar are lithium for depressive episodes in bipolar disorder, Divalproex for manic or mixed episodes in bipolar disorder, lurasidone and aripiprazole for schizophrenia.

FAQs: how long does it take for Vraylar to work?

Can Vraylar be used for Anxiety?

Unlikely, it is an antipsychotic drug that is used for the treatment of Schizophrenia and Mood Disorders. It’s not approved yet for the treatment of Anxiety Disorder. Benzodiazepines and some antidepressants are the use of treatment of Anxiety Disorders.

Is Vraylar a controlled substance?

No, it is not a controlled substance.

What symptoms does Vraylar treat?

It is basically used for the treatment of schizophrenic symptoms such as hallucination, delusion and other bipolar disorder’s symptoms.

Is Vraylar an SSRI?

No, it is not an SSRI. SSRI is a type of Antidepressant while Vraylar is a Second-generation Antipsychotic Medication.

Can Vraylar treat Major Depression?

Yes, it is possible to use Vraylar for treatment of Depression in Bipolar Disorder however, not yet approved for treatment for Major Depression.

Does Vraylar cause Sexual side effects?

No, it is an antipsychotic medication that is not known for any kind of sexual side effect. 

How do I take Vraylar?

Vraylar works gradually and one can take it by mouth, with or without food and once a day.

What time of day is best to take Vraylar?

It can be taken at any time of the day however, some people change the timing of the day to take it because of the side effects associated with it.

Can you lose weight on Vraylar?

No, it is nor likely to cause weight loss.

Does Vraylar help you sleep?

Yes, it is reported that Vraylar does induce sleep and make the person drowsy.

Is Vraylar a good drug?

Yes, it is rated by the user or consumer to be a good drug with its positive effect on treatment as well as eradication of symptoms. 

Can you drink alcohol while taking Vraylar?

No, it’s always advisable not to consume alcohol and alcohol-containing drinks when on the medication. Consuming such drinks along with the medication result in severe and serious side effects. One will feel tired, lethargic and drowsy when both of these are taken in combination.

Is Vraylar safe?

Yes, it is safe and well-tolerated by people and also found to be effective in the treatment of the bipolar disorder, schizophrenia and manic episodes in bipolar disorders.


In this article, we have answered the question, “ how long does it take for Vraylar to work”, Vraylar, precaution to be taken before medication, side effects of it, the working mechanism of the medication, dosage, alternative to Vyalar, Interaction with other drugs, overdose effect and concluded with some FAQs concerning the topic.

For further detail and in-depth information, refer to following sites


Allergan. (2020). Why VRAYLAR. Vraylar. (2020, 7 27). How long does it take for Vraylar to work?

Marshall, H. (2020, 7 19). Vraylar (cariprazine). MedicalNewsToday.

Medscape. (2019). cariprazine (Rx). Medscape.

WebMD. (2019). Vraylar. WebMD.

What was missing from this post which could have made it better?

Leave a Reply

Your email address will not be published.